George Sandusky Selected Research

PR5-LL-CM01

6/2017

Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers.

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George Sandusky Research Topics

Disease

23	Neoplasms (Cancer) 03/2022 - 07/2004
5	Inflammation (Inflammations) 03/2022 - 12/2002
4	Breast Neoplasms (Breast Cancer) 11/2021 - 01/2018
4	Carcinogenesis 01/2020 - 11/2010
3	Pancreatic Neoplasms (Pancreatic Cancer) 08/2021 - 01/2017
3	Cachexia 01/2021 - 12/2017
3	Plexiform Neurofibroma 11/2020 - 01/2020
3	Neoplasm Metastasis (Metastasis) 01/2018 - 03/2005
2	Colorectal Neoplasms (Colorectal Cancer) 03/2022 - 06/2017
2	Leukemia 01/2022 - 04/2002
2	Neurofibromatoses (Neurofibromatosis) 11/2020 - 01/2020
2	Prostatic Neoplasms (Prostate Cancer) 02/2011 - 03/2005
2	Thrombosis (Thrombus) 04/2005 - 12/2002
1	Juvenile Myelomonocytic Leukemia 01/2022
1	Hypoxia (Hypoxemia) 08/2021
1	Atrophy 01/2021
1	Fibromyalgia (Fibrositis) 01/2021
1	Neurofibromatosis 1 (Neurofibromatosis Type I) 01/2020
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2020
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2019
1	Neurilemmoma (Schwannoma) 01/2019
1	Colonic Neoplasms (Colon Cancer) 10/2015
1	Weight Loss (Weight Reduction) 09/2011
1	Body Weight (Weight, Body) 09/2011
1	Plasmacytoma 08/2010
1	Multiple Myeloma 08/2010

Drug/Important Bio-Agent (IBA)

4	Proteins (Proteins, Gene)FDA Link 03/2022 - 10/2015
4	Pharmaceutical PreparationsIBA 01/2022 - 12/2017
4	Phenobarbital (Luminal)FDA Link 11/2021 - 01/2018
3	Estrogen ReceptorsIBA 01/2021 - 01/2018
3	Monomeric GTP-Binding ProteinsIBA 11/2020 - 01/2020
2	RNA (Ribonucleic Acid)IBA 01/2022 - 08/2021
2	Phosphotransferases (Kinase)IBA 01/2019 - 01/2017
2	Hormones (Hormone)IBA 01/2019 - 01/2018
2	Protein CIBA 03/2007 - 12/2002
1	Dyneins (Dynein)IBA 03/2022
1	Antineoplastic Agents (Antineoplastics)IBA 01/2022
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022
1	Oxygen (Dioxygen)IBA 01/2022
1	Small Cytoplasmic RNAIBA 08/2021
1	devimistatIBA 08/2021
1	LipidsIBA 01/2021
1	Interleukin-6 (Interleukin 6)IBA 01/2021
1	Chemokine CCL11IBA 01/2021
1	PalmitatesIBA 01/2021
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2020
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 12/2019
1	TOR Serine-Threonine KinasesIBA 01/2019
1	Glutamine (L-Glutamine)FDA Link 01/2019
1	Estrogens (Estrogen)FDA Link 01/2019
1	CaspasesIBA 01/2019
1	Estrogen Receptor Modulators (Antiestrogen)IBA 01/2019
1	Amino Acids FDA Link 01/2019
1	Neurofibromin 2 (Merlin)IBA 01/2019
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2019
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2019
1	Everolimus FDA Link 01/2019
1	Progesterone Receptors (Progesterone Receptor)IBA 01/2019
1	LigandsIBA 01/2018
1	Histone DemethylasesIBA 01/2018
1	Biomarkers (Surrogate Marker)IBA 12/2017
1	CytokinesIBA 12/2017
1	ChemokinesIBA 12/2017
1	PAX7 Transcription FactorIBA 12/2017
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 10/2017
1	Polo-Like Kinase 1IBA 10/2017
1	PR5-LL-CM01IBA 06/2017
1	Small Interfering RNA (siRNA)IBA 06/2017
1	Protein-Arginine N-Methyltransferases (Methyltransferase, Protein Arginine)IBA 06/2017
1	GSK3235025IBA 06/2017
1	Aurora Kinase AIBA 01/2017
1	Connective Tissue Growth FactorIBA 11/2015
1	Serine (L-Serine)FDA Link 10/2015
1	Y-Box-Binding Protein 1IBA 10/2015
1	Indicators and Reagents (Reagents)IBA 06/2015
1	Folate Receptor 1IBA 06/2015
1	Protein Isoforms (Isoforms)IBA 06/2015
1	Folic Acid (Vitamin M)FDA LinkGeneric 06/2015
1	Monoclonal AntibodiesIBA 06/2015
1	salicylhydroxamic acid (SHAM)IBA 09/2011
1	LY 2181308IBA 02/2011
1	OligonucleotidesIBA 02/2011
1	SurvivinIBA 02/2011
1	Docetaxel (Taxotere)FDA Link 02/2011
1	Antisense OligonucleotidesIBA 02/2011
1	Paclitaxel (Taxol)FDA LinkGeneric 02/2011
1	Gemcitabine FDA Link 02/2011
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 11/2010
1	Dextrans (Dextran)FDA Link 11/2010
1	benzocycloheptapyridineIBA 11/2010
1	2- amino- 1- methyl- 6- phenylimidazo(4,5- b)pyridineIBA 11/2010
1	Cyclin D1IBA 11/2010
1	Aurora KinasesIBA 08/2010
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 08/2010
1	ENMD 2076IBA 08/2010
1	NitrogenIBA 03/2007

Therapy/Procedure

6	Therapeutics 03/2022 - 02/2011
1	Drug Therapy (Chemotherapy) 01/2022
1	Lasers (Laser) 01/2020
1	Ligation 03/2007